HEXANE SOLUBLE BIOACTIVE COMPONENTS OF Chenopodium murale STEM
HEXANE SOLUBLE BIOACTIVE COMPONENTS OF Chenopodium murale STEM
Syeda Fakehha Naqvi1, Iqra Haider Khan1 and Arshad Javaid1
ABSTRACT
Nettle leaf goosefoot (Chenopodium murale L.) is a common winter weed of Chenopodiaceae. Studies have shown that extracts of this weed possess antioxidant, antimicrobial, larvicidal and nematicidal activities. In the present study, n-hexane soluble fraction of methanolic stem extract of this weed was subjected to GC-MS analysis to identify various biologically active constituents. There were 28 compounds in this fraction. Major compounds included oleic acid (16.55%), palmitic acid (11.22%), β-sitosterol (9.63%), hexadecanoic acid (7.71%) and methyl oleate (5.90%). Other prominent compounds were piperine (4.75%), nonacosane (4.69%), monoplalmitin (4.21%), γ-sitosterol (3.91%), methyl linoleate (3.88%), neocurdione (3.86%) and ethanonone (3.25%). The compounds such as stigmasterol (2.92%), 1,4-benzenedicarboxylic acid (2.78%), tetracosanoic acid (1.19%), stearic acid (1.36%), tridecanoic acid (1.35%), tridecanal (1.30%), phytol (1.29%), docosanoic acid, methyl ester (1.23%), octadecanoic acid (1.20%), 4-pyrimidinecarboxylic acid (1.05%), 2-hydroxy-2-phenylbutanamide (0.91%), hexacosanoic acid (0.76%), cholestrol (0.61%), methyl octacosanoate (0.55%) and tetracosanoic acid (0.30%) were present in low concentrations. A thorough literature survey showed that most of the identified compounds possessed antifungal and/or antibacterial properties while very few of them also possessed antioxidant potential. This study concludes that n-hexane soluble fraction of methanolic stem extract of C. murale is a big storehouse of antimicrobial compounds.
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