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Evaluation of Proinflammatory Cytokines in Arsenic Induced Hepatotoxicity In Vivo

Evaluation of Proinflammatory Cytokines in Arsenic Induced Hepatotoxicity In Vivo

Ozdan Akram Ghareeb1*, Goljameen Midhat Abdulla1, Sanaz Sheikhzadeh2

1Department of Pharmacy, Medical Technical Institute, Northern Technical University, Iraq; 2Department of Microbiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

 
*Correspondence | Ozdan Akram Ghareeb, Department of Pharmacy, Medical Technical Institute, Northern Technical University, Iraq; Email: [email protected]

Figure 1:

Toxicity of arsenic on oxidative stress indicators in experiment groups (n = 6): A) MDA, B) TAC, and C) GSH. ns: indicates not significant, while symbol* indicate significant as follows: **: at (p < 0.01), ***: at (p < 0.001) ****: at (p<0.0001).

Figure 2:

Toxicity of arsenic on hepatic enzymes levels: A) ALT, B) AST, C) ALP, and D) GGT in experiment groups (n= 6). symbol* indicate significant as follows: ***: at (p < 0.001) ****: at (p<0.0001).

Figure 3:

Toxicity of arsenic on serum TNF-α level in experiment rats (n=6/group). ****: significant at (p<0.0001).

Figure 4:

Toxicity of arsenic on serum IL-1β in experiment rats (n =6 /group). ****: significant at (p<0.0001).

Figure 5:

Toxicity of arsenic on serum IL-6 in experiment rats (n=6 /group). ***: significant at (p < 0.001) ****: significant at (p<0.0001).

Journal of Animal Health and Production

November

Vol. 12, Sp. Iss. 1

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