Evaluation of Oxidative Status and Inflammatory Changes in Naturally Occurring Canine Visceral Leishmaniasis
Evaluation of Oxidative Status and Inflammatory Changes in Naturally Occurring Canine Visceral Leishmaniasis
Tünay Kontaş Aşkar1,*, Şinasi Aşkar1, Olga Büyükleblebici2 and Murat Güzel3
A, changes in MDA levels in dogs with VL and healthy controls. There is a significant increase in CVL group (P<0.001) when compared with the control group. MDA: malondialdehyde, CVL: canine visceral leishmaniasis; B, changes in antioxidant defense in dogs with VL and healthy controls. In CVL group, there is a significant reduce in TAC (P<0.05) and GSH (P<0,01) levels when compared with the control group. TAC, total antioxidant capacity; GSH, glutathione; CVL, canine visceral leishmaniasis.
A, the correlation of MDA and TAC level in dogs with visceral leishmaniasis. Pearson’s rank correlation coefficient was r = -0.618, P<0.05; B, the correlation of MDA and GSH level in dogs with visceral leishmaniasis. Pearson’s rank correlation coefficient was r = -0.492, P<0.001.
A, the correlation of TNF-α and NO level in dogs with visceral leishmaniasis. Pearson’s rank correlation coefficient was r = 0.812, P<0.001; B, the correlation of TNF-α and MPO level in dogs with visceral leishmaniasis. Pearson’s rank correlation coefficient was r = 0.674, P<0.01; C, the correlation of TNF-α and ADA level in dogs with visceral leishmaniasis. Pearson’s rank correlation coefficient was r = 0.432, P<0.05.d); D, the correlation of TNF-α and IL-1β level in dogs with visceral leishmaniasis. Pearson’s rank correlation coefficient was r = 0.801, P<0.001.
