Enhanced Protection and Blocked Viral Shedding for Broiler Chickens in Challenge with Newcastle Disease Virus Genotype VII by Generation of Oil Inactivated Vaccine Antigenically-Matched to The Endemic Virus in Egypt
Sameh Abdel-Moez Ahmed Amer1*, Aly Mohammed Ghetas1, Asmaa Mahmoud Maatouq1, Hagar Magdy Ahmed1, Khaled Mohamed El-Bayoumi1, Mohamed Abd El-Rahman Bosila1, Ahmed Ali El-Shemy2
1Department of Poultry Diseases, Veterinary Research Institute, National Research Centre, P.O. Code 12622, Dokki, Cairo, Egypt; 2Department of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, P.O. 12622, Dokki, Giza, Egypt.
*Correspondence | Sameh Abdel-Moez Ahmed Amer, Department of Poultry Diseases, Veterinary Research Institute, National Research Centre, P.O. Code 12622, Dokki, Cairo, Egypt; Email:
[email protected]
Figure 1:
Post mortem gross lesions recorded in control group C 3 days pc. A: ulceration and hemorrhages in caecal tonsils. B: Marked splenomegaly. C: severe bloody tracheitis. D: hemorrhagic spots and petechial hemorrhages on proventriculus.
Figure 2:
Results of humoral antibody curve throughout the vaccination course and after challenge with VNDV “NDV-CH-EGY-GIZA-VVTNRC-2021” in all experimental groups A, B, C, and D.
Figure 3:
Oropharyngeal viral shedding at days post-challenge (DPC) in all tested groups shows a decrease and stop of shedding in vaccinated group A with NDV GVII vaccines compared to other tested groups.
Figure 4:
cloacal viral shedding at days post-challenge (DPC) in all tested groups shows a decrease and stop of shedding in vaccinated group A with NDV GVII vaccines compared to other tested groups.