Effect of Basic Periodontal Therapy Combined with Probiotics on Oral Microecology and Blood Sugar Control in Patients with Diabetes and Periodontitis
Effect of Basic Periodontal Therapy Combined with Probiotics on Oral Microecology and Blood Sugar Control in Patients with Diabetes and Periodontitis
Bin Hu1*, Jianchang Qu2, Tenglong Han3 and Jun Leng1
ABSTRACT
To explore the effect of basic periodontal therapy combined with probiotics on oral and intestinal flora, inflammatory factors and blood sugar control in patients with diabetes and periodontitis. A total of 72 diabetic patients with periodontitis who were treated in our hospital were taken as the expirmental objects, as the control group (n=36) and the study group (n=36). Patients in the control group received normal diabetes treatment and basic periodontal treatment, and the study group received probiotic treatment on the basis of the control group. The differences in oral and intestinal flora between the two groups of study subjects were compared, and changes in inflammatory factors, oxidative stress molecules, and blood glucose control related indicators were detected in each patient. There was no statistical difference in gender distribution, age distribution, BMI and HbA1c between the control group and the study group before treatment (P>0.05). After treatment, the PI (P=0.000), GI (P=0.000), PPD (P=0.031), and CAL (P=0.022) of the study group with diabetes and periodontitis were significantly different from the control group. The basic periodontal treatment combined with probiotics has a significant effect on the oral and intestinal flora, inflammatory factors and blood sugar control of patients with diabetes and periodontitis.
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