Discovering the Potential of Teak, Turmeric, and Ginger in Broiler Chicken Gut Health: A Network Biology Perspective on IL-6 Inhibition
Discovering the Potential of Teak, Turmeric, and Ginger in Broiler Chicken Gut Health: A Network Biology Perspective on IL-6 Inhibition
Feri Eko Hermanto1, Yuli Frita Nuningtyas1, Filoza Marwi1, Fajar Shodiq Permata2, Agus Susilo1, Muhammad Halim Natsir1*
Biological network topology contains proteins involved in mucosal immunity, digestive health, and proteins involved in mucosal immunity and digestive health.
Identification of the level of importance of a protein in a biological network using 11 Cytohubba algorithms (A) and a summary of the proteins that consistently have the highest scores (B).
Interaction chemistry among selected compounds according to the molecular docking analysis.
Structural stability of selected complexes according to the value of RMSD backbone atom (A), RMSF of per-residue (B), binding free-energy estimations (C), RMSD of ligand conformation (D), and the number of hydrogen bonds (E).
