Determination of Biologically Active Compounds in Methanolic Extract of Flowers of Senna alata through GC-MS Analysis
Determination of Biologically Active Compounds in Methanolic Extract of Flowers of Senna alata through GC-MS Analysis
Malik F.H. Ferdosi1, Arshad Javaid2*, Muhammad Samiullah1, Zeeshan Mutahir3 and Tajamal Hussain4
ABSTRACT
Senna alata (L.) Roxb. (synn. Cassia alata L.) is a traditional medicinal legume native to Argentina that grows as a wild plant in Pakistan. The present study was conducted for GC-MS analysis of C. alata flowers to identify possible bioactive compounds. Twelve compounds were recorded in the methanolic extract with hexadecanoic acid, 15-methyl-, methyl ester as the most abundant ones with 29.78% peak area. Other compounds were linolenic acid methyl ester (15.84%), guaiacol (9.48%), 2-cyclopenten-1-one, 2-hydroxy-3-methyl- (8.56%), 2-cyclopenten-1-one, 3-methyl- (7.73%), butanal, 3-hydroxy- (6.19%), phenol, 4-ethyl- (4.83%), aziridine, 1-(2-methyl-1-propenyl)- (4.50%), 2-cyclopenten-1-one, 2,3-dimethyl- (3.52%), benzene, 1-ethenyl-4-methoxy- (3.29%), indole (3.64%), benzaldehyde, 2-methyl- (2.57%). A literature survey revealed that some compounds viz. linolenic acid, methyl ester; hexadecanoic acid, 15-methyl-, methyl ester; benzaldehyde, 2-methyl-; guaiacol; and 2-cyclopenten-1-one, 2-hydroxy-3-methyl-possess various biological properties such as antibacterial, antifungal, acaricidal, antioxidant, anticancer, nematicidal, antiacne, insectifuge, antiarthritic, antihistaminic, anti-inflammatory and antieczemic hepatoprotective.
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