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Comparison of the Ameliorative Effects of Qing Zhi Zhi Ke Formula and Azithromycin on Mycoplasma pneumoniae Pneumonia in Mice

Comparison of the Ameliorative Effects of Qing Zhi Zhi Ke Formula and Azithromycin on Mycoplasma pneumoniae Pneumonia in Mice

Ou-Mei Hao1*, Xue-Feng Wang1, Zhi-Jun Yue1, Chun-Hong Nan1,Yan Yu1,Tong Zhang2,Yu-Feng Liu3 and Xue Zhao1

1Affiliated Hospital to Liaoning University Traditional Chinese Medicine, Shenyang, China,110032.
2Liaoning University Traditional Chinese Medicine, Shenyang, China, 110032.
3The Fourth Hospital to Liaoning University Traditional Chinese Medicine, Shenyang, China,110101

*      Corresponding author: 24569573@qq.com

Fig. 1.

Effects of QZZKF on morphological changes in the lung tissues of mice. The inferior lobe of the right lung was harvested after the final exposure after five days of treatment; sections were stained with hematoxylin and eosin (200×). Black arrow, infiltration of inflammatory cells. Yellow arrow, atelectasis and alveolar collapse.

Fig. 2.

QZZKF regulated SP-A, B7-H3, IL-12, and IL-13 expression levels in the lung tissues of mice. Data are presented as the mean ± SD (n = 8–10). *p < 0.05 compared to the control group; #p < 0.05 compared to the model group; and △p < 0.05 compared to the AZM group.

Fig. 3.

Gene expression levels of SP-A, B7-H3, IL-12, and IL-13 in the lung tissues of mice. Data are presented as the mean ± SD (n = 8–10). *p < 0.05 compared to the control group; #p < 0.05 compared to the model group; and △p<0.05 compared to the AZM group.

Pakistan Journal of Zoology

December

Vol. 53, Iss. 6, Pages 2001-2521

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