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Characterization of very Virulent Infectious Bursal Disease Virus in Egypt during the Period 2019-2020

Characterization of very Virulent Infectious Bursal Disease Virus in Egypt during the Period 2019-2020

Mai M. Dawood*1, Mohamed Fawzy2 and Mohamed S. Elshahidy3

1Department of Virology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt, Postal address Egypt – Ismailia (41522); 2Department of Virology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt; 3Department of Virology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.

*Correspondence | Mai M. Dawood, Department of Virology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt. Postal address Egypt – Ismailia (41522); Email: [email protected] 

ABSTRACT

Infectious bursal disease virus (IBDV) is a highly contagious disease of young chickens, that results in bursal necrosis and severe damage of the immune system. IBDV remarkably persist to affect the poultry industry in Egypt. Hence this study was done to identify and characterize very virulent Infectious Bursal Disease virus in Egypt during the period 2019-2020. bursal samples were collected from 8 vaccinated broiler flocks exhibited high mortality rates and bursal lesions in al-El-Fayoum province, Egypt during 2019 and 2020. Reverse transcription PCR was used to detect IBDV in clinical samples by amplification of the hyper variable region (HVR) of VP2 gene. Genetic analysis of the PCR amplicons has revealed that 3 samples belonged to very virulent IBDV (vvIBDV). The genotyping of Egyptian vvIBDv indicate progressive evolution compared with previously isolated strains which indicates persistence of vvIBDv in Egyptian poultry environment. In conclusion, theses data reveal the success and nonstop evolution of the vvIBDv in the Egyptian environment. This is why we must do further analysis in result of the nature of the viruses.

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Journal of Virological Sciences

July

Vol. 3, Iss. 1

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