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Cardio-Protective Effect of Coenzyme Q10 Against Nitrofurantoin-induced Cardiotoxicity in Rabbits

Cardio-Protective Effect of Coenzyme Q10 Against Nitrofurantoin-induced Cardiotoxicity in Rabbits

Mohammed Haider Asker1*, Yahya Fawzi Hashim2, Huda Hamid Mohsen3

1Department of pharmacology and toxicology. College of pharmacy, Mustansiriyah University. Baghdad, Iraq; 2College of Veterinary Medicine, University of Baghdad, Iraq; 3Industrial Research and Development Center/ Veterinary Drugs Research and Production Center.

 
*Correspondence | Mohammed Haider Asker, Department of pharmacology and toxicology. College of pharmacy. Mustansiriyah University. Baghdad, Iraq; Email: [email protected]

Figure 1:

Experimental design used in this study.

Figure 2A:

Section in normal cardiac muscle architecture in control group (G1); 2B: Section in the heart of group 2 shows no mononuclear cells infiltration between cardiac muscle; 2C: Section in the heart of group 2 shows necrotic cardiac muscle with vacuole of fatty droplets; 2D: Section in the aorta of G4 group shows vacuolation in subintima (H andE stain 400X).

Advances in Animal and Veterinary Sciences

November

Vol. 12, Iss. 11, pp. 2062-2300

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