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CHARACTERISTICS AND EFFICACY OF ULTRAFAST LASER PULSES FOR BIOMEDICAL APPLICATIONS

Bibi Safia Haq1,2, Shahnaz Attaullah3, Abdul Shakoor4, Hidayat Ullah Khan5, Khan Alam5, Kausar Shaheen1 

1 Department of Physics,JCW, University of Peshawar,Khyber Pakhtunekhwa, Pakistan
2 Department of Physics & Materials, University of Hull, Hull, HU6 7RX, United Kingdom
3 Department of Chemistry, JCW, University of Peshawar, Khyber Pakhtunekhwa, Pakistan
4 Department of Materials, SAACME, Loughborugh University, LE11 3TU, United Kingdom
5 Department of Physics University of Peshawar, Khyber Pakhtunekhwa, Pakistan 

ABSTRACT

For the fabrication of three dimensional cell scaffolds, femtosecond laser irradiation at 800nm was used for
biomedical applications. The femtosecond laser system was also used to fabricate a bricks and mortar structure in
keratin films to investigate skin structures for different cream absorption. The laser characterised here is Spectra
Physics, Hurricane X. This is a complex laser system consisting of a seed laser and a regenerative amplifier. It is
important to have knowledge of these characteristics to be able to predict the transport of the beam through various
optical elements and also to analyse the subsequent interaction with materials. The whole optical intensity profile in
two dimensional space of a laser beam i.e. across the beam radius and its detailed shape has been measured and it
has been demonstrated that Ti: sapphire laser system has the ability to fabricate three dimensional structures for biomedical
applications. Tissue scaffolds have been prepared with different pore sizes suitable for application in different
living tissues. Polymerisation based on a direct write system to build up solid polymeric material for the fabrication
of three dimensional cell scaffolds can be achieved. By tailoring the optical system and making use of a relatively
weak absorption cross-section we have been able to manufacture deep structures in a single pass of the laser light. 

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Journal of Engineering and Applied Sciences

December

Vol. 42, pp. 01-48

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