Biochemical, Hematologic and Oxidative Stress Biomarkers Investigation in Infected Native Breed Calves with Foot and Mouth Disease virus Serotype A
Biochemical, Hematologic and Oxidative Stress Biomarkers Investigation in Infected Native Breed Calves with Foot and Mouth Disease virus Serotype A
Ramy E. El-Ansary1, Ahmed R. Sofy2, Mohamed A. M. El-Tabakh3, Ahmed F. Afify4, Mostafa El-Gaffary5, Mohamed I. Oraby6*, Mohammed A. Elkhiat6
ABSTRACT
This paper presents a comprehensive analysis of biochemistry patterns in cattle during infection with Foot-and-mouth Disease Virus (FMDV) serotype A during FMD outbreaks in 2018 and 2023 in Giza governorate, Egypt. The study investigated the effect of FMDV infection on several blood parameters, including hemogram (HB%, PCV%, RBCs, WBC and platelets count), serum biochemical parameters (glucose, cholesterol, ALT, AST, urea, BUN, creatinine, triglyceride, CK-MB, total proteins, albumin and globulin), oxidative marker (MDA), enzymatic antioxidant (catalase), TAC and trace elements (Zn and Cu). The results showed significant changes in these parameters following FMDV infection, indicating the potential for FMDV to cause systemic effects beyond the respiratory and digestive signs. Overall, this study highlights the importance of monitoring blood parameters as a diagnostic tool for FMDV infection in cattle.
Keywords | FMD, Cattle, Egypt, Haemo-biochemical, Antioxidants, Oxidative stress
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February 2025
Adv. Anim. Vet. Sci., Vol. 13, Iss. 2,
