Calotropis procera (Aiton) W.T. Aiton is a medicinal weed of family
Asclepiadaceae. This study was carried out to explore the biochemical profile of C.
procera flowers collected from Southern Punjab region of Pakistan. Methanolic flower
extract of C. procera was subjected to GC-MS analysis. There were 30 compounds
identified in this extract. The predominant compound was γ-sitosterol with 15.39%
peak area. Other abundantly occurring compounds included stigmasterol (9.22%),
9,12-octadecadienoic acid (Z,Z)-, methyl ester (9.01%), campesterol (8.63%), α-
amyrin acetate (8.25%), β-amyrin (8.09%), hexadecanoic acid, methyl ester
(7.91%), 11-octadecenoic acid, methyl ester (6.15%), and 2-methoxy-4-vinylphenol
(5.66%). Moderately abundant compounds included nonacos-1-ene (2.83%), methyl
stearate (1.57%), pentacosane (1.44%), phytol (1.33%), heptacos-1-ene (1.20%),
heneicosane (1.19%), and 1-hexacosene (1.09%). The remaining less abundant
compounds were present with peak areas less than 1%. Literature survey showed
that the major compounds identified in the flower extract of C. procera possess
various bioactivities including ant-diabetic, anticancer, antihyperglycemic,
antioxidant, antimicrobial and anti-inflammatory.