Antibacterial Sodium Alginate Cosmetic Herbal Electrospun Nanofiber Mask
Antibacterial Sodium Alginate Cosmetic Herbal Electrospun Nanofiber Mask
Ayesha Saeed1*, Farzana Kishwar2, Ahsan Nazir3, Sharjeel Abid4, Muhammad Abiodullah5, and Danial Ali6
ABSTRACT
Sodium Alginate (SA) and polyvinyl alcohol (PVA) have earned industrial recognition due to its biocompatible nature. Traditionally, Musa Acuminata (MA) and Hibiscus Rosa Sinensis (HRS) leaves famous for its medicinal value as they contain phytochemicals such as triterpenoids, polyphenols, flavonoids, and alkaloids. Keeping in view and get benefit from their fruitful properties the aim of the study was to develop antibacterial dry sheet nanofiber mask loaded with leaf extracts of MA and HRS as antibacterial agents in SA/PVA nanofibers through electrospinning method, which was just wet before its application. Leaf extracts were used at three concentration levels (0.5, 1, and 1.5 %). Scanning Electron Microscope (SEM) images confirmed the formation of optimized nanofibers with diameter range from ±49 to ±545 nm. It was observed that addition of leaf extract increased the solution conductivity and decrease the surface tension and viscosity. Chemical reactions and presence of functional groups of SA, PVA, HRS and MA were studied by Fourier Transform Infrared Spectroscopy (FTIR). Crystallinity decreased as the SA and leaf extract loaded into the PVA nanofibers as studied through X-ray diffraction (XRD). SAMA nanofibers exhibited highest antibacterial properties against Staphylococcus aureus (gram positive bacteria) than Escherichia coli (gram negative bacteria), while SAHRS nanofibers showed moderate value against both bacteria. It was concluded that prepared antibacterial nanofiber cosmetic mask has an excellent application in medical cosmetic industry.
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