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Ameliorative Effects of Monoammonium-Glycyrrhizinate on Liver Lipid Metabolism and Antioxidant Capacity in Laying Hens

Ameliorative Effects of Monoammonium-Glycyrrhizinate on Liver Lipid Metabolism and Antioxidant Capacity in Laying Hens

Mengke Wang1, Shucheng Huang2, Cai Zhang1*, Haizhou Gong1
Shunan Cuan1, Shuaishuai Wang1, Qi Shao1, Wenhao Xu1, Sudan Meng1
Pengfei Li1, Yuqin Wang1 and Zijun Yang1

1Laboratory of Environment and Livestock Products, Henan University of Science and Technology, Luoyang 471023, P. R. China. 
2College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. China
 
Mengke Wang and Shucheng Huang contributed equally to this work.

*      Corresponding author: zhangcai@haust.edu.cn

Fig. 1.

Histological analysis of the livers and hepatic lipids.

Fig. 2.

Observation of hepatocyte apoptosis by TUNEL staining. Cells with nuclei that stained dark brown were considered to be TUNEL positive. A) The control group; B) 25 mg/L MAG group; C) 50 mg/L MAG group; D) 100 mg/L MAG group; E) 200 mg/L MAG group. In the MAG groups, decreased apoptotic cell number was seen compared to the control group. Scale bar=200μm.

Fig. 3.

Effect of different levels of MAG in serum parameters of laying hens. Data represent means±SD, one-way ANOVA, and different letters represent statistically significant differences (P < 0.05). ALT, alanine aminotransferase; AST, aspartate transaminase; ALP, alkaline phosphatase; T-AOC, total antioxidant capacity; T-SOD, total-superoxide dismutase; MDA, malondialdehyde; CAT, malondialdehyde; TG, serum triglycerides.

Pakistan Journal of Zoology

December

Vol. 53, Iss. 6, Pages 2001-2521

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