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The Point behind Translation of Aptamers for Point of Care Diagnostics

The Point behind Translation of Aptamers for Point of Care Diagnostics

Tarun Kumar Sharma, John G. Bruno and William C. Cho

Centre for Biodesign and Diagnostics, Translational Health Science and Technology Institute, Faridabad, Haryana-121001, India; 2AptaBharat Innovation Private Limited, Translational Health Science and Technology Institute Incubator Haryana-121001, India; 3Operational Technologies Corporation, 4100 NW Loop 410, Ste, 230, San Antonio, TX 78264, USA; 4Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong.

tarun@thsti.res.in, aptabharat@gmail.com.

ABSTRACT

Owing to the high affinity and specificity in recent years aptamers, have emerged as competitive tools with the potential to replace antibodies in many diagnostic formats. The aptamer industry is continuously growing to create space in research and diagnostics markets. However, translation of aptamer in several applied disciplines is still lagging behind as compared to antibodies. In this article, we discuss the translational aspects of aptamers, current potential of aptamers and strategies to create the “bench-to-bedside” translation of aptamer technology.

 

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Pakistan Journal of Zoology

August

Vol. 52, Iss. 4, Pages 1225-1630

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