The current study focus on the response of different tomato cultivars against aphid, Myzus persicae (Sulzer) and its associated natural enemies at Agricultural Research Institute (ARI) Mingora Swat, during the growing season 2017. The tomato cultivars include Swat local, Rio-Grande early, U-Grande, Rio-Grande late, Tomato BSS-30, 87-5 China and Roma VF. These varieties were sown in Randomized Complete Block Design with three replications. Results of this research showed that aphid population remained constant on different cultivars throughout the experiment. The lowest (3.30 aphids leaf-1) mean number of aphids were recorded on 87-5 China followed by U-Grande (3.72 aphids leaf-1), Tomato BSS-30 (4.22 aphids leaf-1), Roma VF (4.45 aphids leaf-1), Rio-Grande late (4.67 aphids leaf-1) and Swat local (5.11 aphids leaf-1). While, the highest (5.40 aphids leaf-1) were recorded on Rio-Grande early. Initially the population of aphid was found low followed by increase with the passage of time and reached to peak till week 4th (5th May). Then, the population of aphids started declining and lowest population was observed in week 8th (2nd June). Data regarding the natural enemies revealed that, the population of natural enemies was low at the beginning, increased till week 4th (5th May) where highest population was recorded. Afterwards declined trend was observed in the population of natural enemies. The lowest population of natural enemies were recorded in week 8th (2 June). The highest yield (5.70 t ha-1) was obtained from 87-5 china cultivar followed by Rio-Grande late (5.58 t ha-1), Roma VF (5.32 t ha-1), Tomato BSS-30 (5.15 t ha-1), U-Grande (5.11 t ha-1), Swat local (4.94 t ha-1) and lowest yield (4.70 t ha-1) was recorded from Rio-Grande early. Tomato cultivar (87-5 china) was recommended for to use in IPM.