Advances in Animal and Veterinary Sciences
Silver Nanoparticles Embedded Photosensitive Silicon as Catheter Materials
Swati Dahiya1*, Neha Bhardwaj2, Sanjeev Bhardwaj2, Jyotsana Mehta2, Arun Sehgal, Minakshi Prasad3
1Department of Veterinary Microbiology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar- 125004, Haryana; 2Central Scientific Instrumentation Organisation (CSIO), Sector-30C, Chandigarh-160030; 3Department of Animal Biotechnology, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar-
125004, Haryana, India.
*Correspondence | Swati Dahiya, Lala lajpat Rai University of Vetrinary and Animal Sciences, Hisar, Haryana, India; Email: swatidahiya@yahoo.co.in
Abstract
Biofilm growth on catheter surface is a challenge for various biomedical applications. Microbial colonization on catheter’s surface leads to many infections. Silicone polymer is a routine material for catheter fabrication. In the present work, silver nanoparticles (NPs) and photosensitive non-toxic dye toluidiune blue (TB) embedded silicon polymer is synthesised by swell encapsulation method and characterised by UV spectroscopy. The embedded polymer showed high bactericidal activity against gram-positive bacteria Staphylococcus aureus (S. aureus) and gram-negative Proteus mirabilis (P. mirabilis) with least leaching effects which suggests their usage as a new weapon to fight catheter related infections.
Keywords | Catheter, Photosensitizer dye, Toluidine blue, Silver nanoparticles, Bactericidal
