Issue · 2014
Vol. 1, Iss. 1, Pages 1-16
3 articles · pp. 1-16 · All issues →
ReviewAptamers as an Emerging Player in Biology
Aradhana Chopra, Ravi Shukla, Tarun Kumar Sharma
Aptamers are single stranded nucleic acid molecules that are considered as chemical rival of antibodies. They are generated through an in vitro evolution process called SELEX. These single stranded nucleic acid aptamers can acquire various secondary and tertia…
25 Aug 2014
CommentaryAptamers and SELEX: Tools for the Development of Transformative Molecular Recognition Technology
Maureen McKeague, Maria C. DeRosa
Aptamers, single stranded nucleic acid-based molecular recognition elements, are generated through an in vitro evolution process called SELEX. The selection of aptamers with optimal specificity and high affinity remains a challenge, leading to the recent emerg…
25 Aug 2014- Commentary
Aptamers as Viral Replication Antagonists
Nicola J. Stonehouse
Aptamers are nucleic acids, selected in vitro to specifically bind target molecules. They can therefore be useful as molecular tools and also as novel therapeutic agents. This commentary describes RNA aptamers selected to bind to the RNA-dependent-RNA polymera…
13 Sept 2014