Multiple sclerosis (MS) is an inflammatory disease of the brain and spinal cord where it damages the myelin sheath
protecting the neurons. Many environmental and genetic factors have been associated with MS. The aim of this study
is to identify the possible risk factors that are linked to MS in Pakistani population. This study was conducted in
Department of Radiology, Mayo Hospital Lahore from 2013 to 2014. The first hundred patients who came for
reporting MRI of the brain and had positive findings of MS were retrospectively evaluated. Mean age of the patients
was 43.07±13.88 years, with youngest patient as 18 years old and eldest as 65 years. Our study depicted 19% cases
of MS were smokers. 8% of the patients had positive history for viral infections. 8 % of the patient had low level of
serum vitamin D and 30% of the patients had positive family history. Current study shows viral infections, smoking,
and hypovitaminosis D as frequently associated with MS.