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Short Communication · Volume 4, Issue 7, Pages 389–393, 26 July 2016 · Open Access

Case Report on the Treatment of Surgically Debrided Deep Wounds with A New Antioxidant Wound Dressing in Two Dogs

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Journal:
Advances in Animal and Veterinary Sciences
Published:
26 July 2016
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From the article

  • Case Report on the Treatment of Surgically Debrided Deep Wounds with A New Antioxidant Wound Dressing in Two Dogs.
  • In this case report, we present data on the evolution and resolution of two medium-size necrotic wounds of different origin that were treated with surgical debridement followed by a new experimental antioxidant dressing for moist wound care in animals, HR006.
  • No signs of infection were observed, and wound closure was obtained after 7 weeks.
  • At day 3, a marked improvement of the tissue was observed with new healthy granulation tissue covering the entire wound.

Selected from the article's own text.

Abstract

Joan Balasch1, Laura Ramió-Lluch2, Anna Puigdemont3, Begoña Castro4, Felix Bastida5*

1Hospital Veterinari Balmes, Carrer de Balmes, 81, 08008 Barcelona, Spain; 2Laboratorios LETI, Avinguda de Cerdanyola, 92, 08172 Sant Cugat, Barcelona, Spain; 3Universitat Autònoma de Barcelona, Faculty of Veterinary, 08193 Bellaterra, Barcelona, Spain; 4Histocell, Bizkaia Science and Technology Park, 48160 Derio, Bizkaia, Spain; 5Artin Vet Innovative Therapies, Bizkaia Science and Technology Park, 48160 Derio, Bizkaia, Spain.

Abstract | In dogs, large surgical skin wounds are common after tumor resection, trauma or abscesses. In this case report, we present data on the evolution and resolution of two medium-size necrotic wounds of different origin that were treated with surgical debridement followed by a new experimental antioxidant dressing for moist wound care in animals, HR006. Case 1 dog had a deep and wide compression necrosis on the external area of the right hind hock. Case 2 dog had an abscess due to the insertion of plant awns on the right side of the head in the area of the cheek. After systemic antibiotic treatment and surgical debridement, wounds were covered with the experimental antioxidant wound dressing HR006, a matrix of natural galactomannan hydrated with a curcumin and N-acetylcysteine cysteine solution. Dressings were changed 1 to 3 times during the first week, followed by weekly changes for 6 to 7 weeks. In both cases, a healthy granulation tissue appeared very fast that regenerated missing tissue. Re-epithelization borders were also very healthy and quickly covered the affected area. Both cases resolved well within 8 weeks. Moist wound care with an antioxidant dressing for deep and medium-sized wounds produced after surgical debridement and removal of necrotic tissue worked well for prompt evolution and closure of the wounds by second-intention.

Keywords  | Surgical debridement, Dog, Moist wound healing, Oxidative stress, Antioxidants

Acknowledgements

FB has partial funding from the European Social Fund through a grant of the program Torres Quevedo from the Spanish Ministry of Economy and Competitiveness (PTQ-13-06469).

Conflict of Interests

BC and FB work for the company that developed the antioxidant wound dressing.

Authors’ Contribution

LRL, AP, BC and FB designed the study; JB treated the animals and collected the data, and FB and JB drafted the manuscript. All authors reviewed, corrected and improved the manuscript.

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Case Report on the Treatment of Surgically Debrided Deep Wounds with A New Antioxidant Wound Dressing in Two Dogs · ResearchersLinks