Issue · 2024
Issue 1
36 articles · All issues →
ReviewCandidiasis and opportunistic mycosis in human
Habtamu Tedila, Addisu Assefa, Feto Haji
Pathogenic fungi cause serious diseases in humans, plants and animals. These include mainly, Candida spp., Aspergillus spp., Cryptococcus spp., Fusarium spp., and Pneumocytis spp. Candida species cause infections in individuals with deficient immune systems, a…
5 Feb 2025DOI 10.21608/NRMJ.2019.28105- Articles
Burden of fungal diseases in Egypt
Sherif M. Zaki
Fungal diseases cause 1.5 million deaths and cause cutaneous infections to billions of people worldwide every year (Vos et al., 2012; GAFFI. 2015). Egypt is the highest populated country in the Middle East and North Africa region. Due to the fact that many ris…
1 Feb 2025 - Articles
Production of silver nanoparticles (AgNPs) by certain bacterial strains and their characterization
Abo-State M.A.M. Partila A.M
Development of biologically inspired experimental processes for the biosynthesis of nanoparticles (NPs) is an evolving important branch of nanotechnology. In the present work, we studied the potential of four bacterial species for extracellular productio…
1 Feb 2025 - Articles
In vitro inhibitory potential of two synthesized fatty amides derivatives against some microbial pathogens
Fatiha Malki, Abdelkader Touati
In the present study, two amide derivatives with long chains; N-cyclohexyloctamide 1 and N- Phenyldodecanamide (dodecanilide) 2 were synthesized. They were tested in vitro for a wide array of antimicrobial activities against; two Gram positive bacteria (…
5 Feb 2025 - Articles
Screening and interaction between pathogens and antagonistic seed-borne fungi, associated with some organic spices and vegetable crops in Tunisia
Ibtissem Ben Salem, Yosra Abdelkhalek, Houssem Nabli, Neji Tarchoun, Naima Boughalleb-M’Hamdi
Seed-borne pathogenic and antagonistic fungi were isolated from the same organic vegetable and spice seeds (carrot, fennel, broad bean, faba bean, and lettuce), and the interaction between them were studied as a part of a biocontrol assay. In vitro dual…
5 Feb 2025DOI 10.21608/nrmj.2019.28109 - Articles
Isolation, characterization, and detection of antibacterial activity of a bioactive compound produced by marine Bacillus sp. MH20 from Suez Bay, Egypt
Mahmoud Saber Kelany, Ehab Aly Beltagy, Maha Abd El-Fattah Khalil, Mohamed Ahmed El-Shenawy, Wagih Abd El-Fattah El-Shouny
This study focused on isolating and identifying a new bacterial strain from marine water and sediments of Suez bay, Timsah Lake, Egypt; capable of producing a bioactive secondary metabolite. Of the 552 bacterial isolates recovered, only 40 of these isola…
5 Feb 2025 - Articles
Antimicrobial activity of Ricinus comunis, Swietenia mahogani and Crusentia cujete ethanol extracts against multidrug resistant pathogens, recovered from a hospital environment
Mojisola, C. Owoseni, Clara Ginikanwa, Bashiru Sani, Peter Uteh Upla
Medicinal plants have been used as effective approaches to manage multidrug resistant pathogens, including infectious agents that cause nosocomial infections. This study aimed to investigate the antimicrobial potentials of ethanolic extracts of Ricinus c…
8 Feb 2025 - Articles
Antibacterial potency of garlic extract against certain skin pathogenic bacteria
Dadile M. Abdulrahman 1 Abdullahi M. Daskum 1 Kura M. Abdulrahim 1 Abubakar M. Dadile 2 Hajja Amma
The antibacterial potency of garlic extract (Allium sativum) against gram positive and gram negative skin pathogenic bacteria including; Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, and Pseudomonas aeruginosa were studied using ag…
1 Feb 2025 - Articles
Identification of phytopathogens from a taxonomic view, an example of Cryphonectriaceae
Ning Jiang Chengming Tian Xinlei Fan
Plant diseases cause lots of losses worldwide, and pathogens identification is essential during diseases studies. Traditional identification of phytopathogens mainly relied on host information and pathogen morphological characteristics, which limited the…
1 Feb 2025 - Articles
Insight from morphology and phylogeny in species delimitation of Diaporthe
Qin Yang Xinlei Fan
Members of Diaporthe are known as plant pathogens, endophytes or saprobes on a wide range of host plants. Diaporthe species are well-known as the causal agents of many important plant diseases; including root and fruit rots, dieback, stem cankers, leaf s…
1 Feb 2025 - Review
Disease cycle and infection strategies of systemic plant pathogen Botrytis cinerea
Yahaya, S.M, Mardiyya, A.Y, Sakina, S.B et al.
Botrytis cinerea is a ubiquitous filamentous fungal pathogen of a wide range of plant species. This fungus is able to infect all aerial parts of its host plants; where infection may cause enormous damage both during plant growth and in the post-harvest s…
5 Feb 2025DOI 10.21608/nrmj.2019.28106 - Articles
Green synthesis of silver nanoparticles using Portulacaria afra plant extract: characterization and evaluation of its antibacterial, anticancer activities
Taher A. Salaheldin, Ghadir A. El-Chaghaby, Mohamed A. El-Sherbiny
Applications of nanotechnology in different areas of research have expanded over the last years. Silver nanoparticles (AgNPs) have beneficial effects as antimicrobials, antioxidants and/or anticancer. Yet, one of the major limitations of their use was em…
5 Feb 2025DOI 10.21608/nrmj.2019.28107 - Articles
Biodegradation of hydrocarbons by halophilic bacteria isolated from the saltpans of Thoothukudi district, India
Laxmi, Gayathri
Many halophilic microorganisms have evolved unique properties of a considerable biotechnological importance. In this study, two halophilic bacteria were isolated from the solar saltpans of the Thoothukudi district, located in Tamil Nadu, India, and were…
5 Feb 2025 - Articles
Study of population dynamics of Clavibacter michiganensis subsp. michiganensis in exposed and buried crop debris
Ayesha Bibi, Muhammad Junaid, Musharaf Ahmad, Syed Fayaz Ali Shah, Iftikhar Hussain Khalil
The aims of the current work were to determine the effect of burial depth (0, 6, 12 and 18 cm) on the degradation of diseased crop debris, and survival of the debris-borne bacterial inoculum. This study was carried out in two-locations namely; the Agricu…
5 Feb 2025DOI 10.21608/nrmj.2019.28110 - Articles
First report of the association of Genus Chaetomium with roots of Cucurbita maxima
Jonathan D. Hulse
Chaetomium sp. is a fungal genus in the Ascomycota that has a world-wide distribution throughout tropic and temperate regions. Species of Chaetomium are often associated with and classified as both seed-borne and soil- borne fungi, which inhabit a variet…
5 Feb 2025 - Articles
The skin commensal Staphylococcus epidermidis, is a boon or bane?
Emad, M. Abdallah
Skin is an active immune organ, which protects the human internal organs from biotic and abiotic hazards. Staphylococcus epidermidis is a primary bacterial colonizer of the skin and one of the most abundant microorganisms among the other skin microbiome.…
8 Feb 2025 - Articles
Utility of GeneXpert MTB/RIF assay for the diagnosis of pulmonary and extra-pulmonary tuberculosis, A report from Egypt
Enas, M. Hefzy, Mona, I. Ahmed, Abdelrahman, M. Ahmed et al.
Early diagnosis of tuberculosis continues to be a challenge for clinicians. The World Health Organization (WHO) guidelines recommend the application of GeneXpert MTB/RIF in extra-pulmonary tuberculosis (EPTB) diagnosis. This study aimed to test and compa…
8 Feb 2025 - Articles
Utilization of Date palm (Phoenix dactylifera L.) wastes for bioethanol production using Pichia kudriavzevii strains
Folake T. Afolabi, Ibukun E. Ola
Tons of Date palm (Phoenix dactylifera L.) fruit wastes are discarded daily by the date palm processing industries thus leading to serious environmental problems. This study aimed to investigate the potential of date palm fruit wastes as sugary feedstock…
8 Feb 2025 - Articles
Evaluation of the antioxidant and antimicrobial activities of the spent coffee extracts and their applications as natural food preservatives of chicken fillets
Ghadir A. El-Chaghaby, Heba A. Shehta, Sayed Rashad, El-Shaimaa A. Rawash, Heba R. Eid
The present study aimed at evaluating the phytochemical composition, antioxidant, and antimicrobial potentials of spent coffee extracts (SCE) to use these extracts as natural preservatives of food. The effectiveness of SCE in postponing the oxidation and…
8 Feb 2025 - Articles
Association of multiple mutations in NS5A and NS5B genes and resistance to direct-acting antivirals in chronically infected Egyptian patients with Hepatitis C virus Genotype 4a
Gehad M. Mohamed, Ahmed B. Barakat, Marwa M. Gado, Fatma M. Abdallah
Approximately 71 million people worldwide are supposed to have chronic hepatitis C virus (CHCV). New direct-acting antiviral (DAA) medications have been used, which helped successfully in complete treatment of CHCV and achieved a sustained virological re…
8 Feb 2025 - Articles
Aflatoxins and aflatoxigenic fungal contamination of common poultry feed products in Katsina State, Nigeria
Bahauddeen Dandashire Salisu, Ibrahim Raubilu Almajir
This study was conducted to screen the common poultry feed products sold within Katsina State, Nigeria, for the presence of aflatoxigenic fungi and aflatoxins. A total of 15 poultry feed samples from 3 major producing companies were purchased from retai…
5 Feb 2025 - Articles
Biosynthesis of metal nanoparticles using microorganisms and its medicinal applications
Maysaa, T. Alloosh, Walid, I. Khaddam, Adbulsalam, K. Almuhammady
Nanotechnology is one of the most important technologies that enter into multiple fields, as it depends on the synthesis of particles with nano scale called nanoparticles (NPs). Biosynthesis of nanoparticles can be done using plants or microorganisms; h…
8 Feb 2025 - Articles
In vitro inhibition of uropathogenic Escherichia coli biofilm formation by probiotic Lactobacilli isolated from healthy breast fed infants
Zeinab, S. Hashem, Rehab, M. Abd El-Baky
Biofilm forming Escherichia coli bacterium exhibits multiple drug resistance, which is responsible for recurrent urinary tract infections (UTI) that are difficult to eradicate. The work aimed to investigate the antibacterial and antibiofilm activities o…
8 Feb 2025 - Articles
Potentials of the marine microbial enzymes in therapeutics
Syeda Sadaf Wajahat
About 70 % of the surface of Earth is covered with oceans and hosts an enormous variety of environmental, biological, and chemical standings. The marine environment consists of a comprehensive range of animals, plants, and microorganisms, which have sev…
8 Feb 2025 - Articles
Detection of coagulase-positive Staphylococcus and its antibiotics resistance profile, recovered from cattle carcasses of the state of Paraná, Brazil
Gonçalves, da Rosa, Merlini, L.S, Geronimo, Borges et al.
Staphylococcus sp. is a commensal bacterium in humans. Nonetheless, it is considered as an opportunistic microbe, being frequently associated with food poisoning outbreaks and antimicrobial resistance. The purpose of this work was to evaluate the presenc…
5 Feb 2025DOI 10.21608/nrmj.2019.28108 - Articles
Extracellular GroEL Promotes adherence of ΔrhlA mutant to inert surfaces in Pseudomonas aeruginosa
Sebnem Bukavaz
In this study, we investigated the physiological response of inorganic (Pi-PO4) deficiency; which has an increased effect on rhamnolipid production in P. aeruginosa, with respect to virulence and biofilm- related proteins. The proteins were obtained thro…
5 Feb 2025DOI 10.21608/NRMJ.2019.28104 - Articles
Genetic diversity of Fusarium solani f.sp. cucurbitae the causal agent of crown and root rot of watermelon in Tunisia using ISSR markers
Naïma Boughalleb-M’Hamdi, Najwa Benfradj, Ibtissem Ben Salem, Paloma Abad-Campos
Fusarium solani f.sp. cucurbitae (F.s.c.) Snyder and Hansen is one of the most important fungi causing serious damages to the cucurbits production areas in Tunisia. The goal of this investigation was to study the genetic characterization of F. solani f.…
5 Feb 2025 - Articles
Role of the JC Polyomavirus (JCV) and BK Polyomavirus (BKV) in the colorectal cancer of some Egyptian patients
Sherihan Samir, Ahmed B. Barakat, Waled M. El-Senousy, Ahmed A. Abou-Zeid, Omar A. Rabiee
Although several cases and case-control studies reported the prevalence of JC polyomavirus (JCV) and BK polyomavirus (BKV) in tumor tissues of colorectal cancer (CRC) patients as well as in control samples; however, many recent studies did not show the…
5 Feb 2025 - Articles
Interleukin-27 levels and its Polymorphism in Hepatocellular carcinoma associated with Hepatitis C
Nahla Anber, Maysaa El Sayed Zaki, Mona El Wassefy
The prevalence of Hepatocellular carcinoma (HCC) in Egypt represents about 11% of the gastrointestinal tract malignancies. The development of HCC usually is preceded by chronic infections with Hepatitis C virus (HCV). Interleukin-27 (IL27) is implicated…
5 Feb 2025 - Articles
Electro-fermentative production of thermotolerant lipases by electrogenic bacteria isolated from palm oil mill effluents
E.O. Garuba, O.M. Ajunwa, O.S. Oguntomi, A.A. Onilude
This study aimed at assessing the effects of Bio-electrochemical system on the yield of thermostable lipase produced by Bacillus licheniformis S1S2, Bacillus pulmilus S1E23, Bacillus sp. S1E27, and Aeribacillus sp. S1E29. With physiological conditioning…
5 Feb 2025 - Articles
Optimization of cellulase and chitinase enzymes production by plant growth promoting rhizobacteria
Alaa Fathalla Mohammed
The current study aimed to optimize the production of cellulase and chitinase enzymes by plant growth promoting rhizobacteria (PGPR). Bacteria were pre-isolated from soil and identified as; Pseudomonas fluorescens NBRC (KW1), Serratia liquefaciens ATCC…
5 Feb 2025 - Articles
Isolation and full genome sequencing of two human Astroviruses isolated from children in Cairo, Egypt
Ahmed El Taweel, Ahmed Kandeil, Ahmed Barakat, Omar El Faroq, Ghazi Kayali, Mohamed Ahmed Ali
Astroviridae is a diverse family of viruses that are circulating in a wide range of hosts. Diversity of these viruses plays a major role in the emergence of zoonotic diseases. Limited studies were conducted on the prevalence and genetic proprieties of h…
5 Feb 2025 - Articles
Evaluation of in vitro antifungal potential of several fungicides against Alternaria alternata (Fr.) Keissler, the causal agent of potato brown spot in Afghanistan
Abdul, K. Madadi, Hadia Rauf, Mohammad, H. Falahzadah, Ahsanullah Yousufzai et al.
Potato brown spot caused by Alternaria alternata (Fr.) Keissler is one of the most destructive diseases of potato worldwide. The present study was conducted to identify the causal agent, and to test the efficacy of several fungicides with different mode…
8 Feb 2025 - Articles
Breakthroughs in SARS-CoV-2-monoclonal antibodies development
Yusuf Muhammed, Mkpouto Pius, Bashiru Sani, Bulus Timothy, Jafar Usman, Musa Garba
In December 2019, cases of unknown pneumonia-like disease connected to food markets were reported in China. The causative agent was identified as a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV- 2), and the disease which spread all over the…
8 Feb 2025 - Articles
Association of Hepatitis C viral load with liver functions and risk factors among HCV patients, Minia governorate, Egypt
Hala, R. Ahmed, Reham, A. Ibrahem, Rehab, M. Abd El-Baky et al.
Hepatitis C virus (HCV) is one of the blood transmitted hepatitis viruses. HCV infections have been identified as major causes of chronic hepatic diseases, and hepatocellular carcinoma. The aims of the current study were to determine the HCV viral load…
8 Feb 2025 - Articles
In-vitro investigation of biofilm-specific resistance and virulence of biofilm-forming uropathogenic Escherichia coli
Sara A. Alshaikh, Tarek El-Banna, Fatma Sonbol, Mahmoud H. Farghali
Uropathogenic Escherichia coli (UPEC) is the primary etiologic agent of urinary tract infections (UTIs). This study aimed to investigate the difference in antimicrobial susceptibility of UPEC isolates in the planktonic and biofilm states. Important viru…
8 Feb 2025