Pakistan has more than 70 sugar manufacturing industries which are responsible for massive production ofmolasses. Typically the molasses is converted to ethanol through fermentation process. A pilot plant has been designed and fabricated to investigate the effect ofprocess parameters for the sustainable production of ethanol from sugar cane molasses. The effect of various experimental parameters such as fermentation time, molasses solution concentration and its pH during ethanol recovery from sugarcane molasses has been investigated. The interaction effects, optimum conditions, and percent contribution ofeach factor were determined statistically. The maximum ethanol recovery was found to be 24.65 gmlL when pH of molasses solution was 4.5, concentration of molasses solution was 20 gm/kg and fermentation time was 56 hours.