ALT inhibits the growth of glioma xenografts. (A) Survival analysis for animals treated with 0.9% saline or ALT (20mg/kg) (P< 0.01 by log-rank test; n 0.9% saline =12, n ALT =12). (B) Bioluminescence imaging showed the tumor size. (C) H and E staining of sections from mouse brains with U87 xenografts treated with 0.9% saline or ALT (20mg/kg) at 21 days. (D) IHC for YAP, p-YAP, p-EGFR, CD133 and SOX2 in sections from indicated xenografts (scale bar = 100 μm).