Evaluation of the effect of the fructose, the MECL and losartan on the anxiety of rats in open fields. Number of central squares visited (A) and the time spent in the central cells (B) in the open field test. The results are represented by the mean ± SEM (n = 6), the statistical analyses were carried out by unidirectional ANOVA followed by Tukey’s post hoc test; the significance level is. * P <0.05, ** P <0.01, *** P <0.001, C.  Curcuma longa, F. fructose, L. losartan.