The effect of KD on the expression of JAK2 in the CT26+ colon cancer mouse model. (A) The representative expression of p-JAK2 and JAK2 protein tumor tissues and β-actin as the internal control for normalization. (B) Quantitative analysis of p-JAK2/JAK2 ratio in tumor tissues. Each experiment was repeated three times, and all the data were presented as mean ± SEM in each case. Independent-sample T-test was used when different sets of data were compared. Statistically significant differences between different groups were indicated as *p < 0.05, **p < 0.01 and ***p < 0.001.