(A): A section of the kidneys of diabetic rats treated with Empagliflozin showing the occurrence of pathological changes in the cortex area, including shrinkage of the glomerulus (GS), widening of Bowman’s space (BE). While (B) showing increased capsular wall thickness (TW), glomerular necrosis (GN), intraglomerular hemorrhage (GH), death of some glomerular cells (DC), and infiltration. Inflammatory cells A, rupture V, epithelial cell detachment SB, severe bleeding H, congestion of some renal tubules CO (H & E 40x).