Dose-dependent effects of PF915275 (a specific inhibitor of 11β hydroxysteroid dehydrogenase type 1) on the conversion of cortisone to cortisol by bovine endometrial tissue from the follicular stage (Mean ± SEM, n=4 experiments, each performed in triplicate). Endometrial tissues were exposed to PF (0-1000 nM) or PGF (1 µM) combined with cortisone (300 nM) for 4 h. Different superscript letters indicate significant difference (p<0.05) as determined by ANOVA followed by protected least significant difference test (PLSD).