Gene mutation analysis (A) and difference analysis (B) for model samples from TCGA. 

Notes: A: 105 patients samples in cBioPortal online database; NOL3: gene amplification, 1 case; missense mutation, 1 case; STC2: missense mutation, 1 case; GPC1: missense mutation, 4 cases; ENO3: deep deletion, 10 cases; truncation mutation, 1 case; missense mutation, 1 case. B: Red color: normal samples; green color: tumor samples; ***: significant difference at p <0.001.