The spatial structure and conserved domains of CDK16 protein. A, Secondary structure of CDK16 protein. The red, pink, green and blue vertical lines represent extended strand, random coil, beta turn and alpha helix, respectively. B, Tertiary structure of CDK16 protein. The N-terminal, C-terminal, α-helix, β-sheet, β-turn and random coil are highlighted with thick arrows. C, The conserved domains S_TKc (171-452).