Fig. 4.

ALKBH5 modulates ZEB1 to affect EMT of ARPE-19 cells. (A), CCK-8 assay examined cell viability in ARPE-19 cells transfected with sh-NC, sh-ALKBH5#1 or sh-ALKBH5#1+ZEB1 and in TGF-β1-treated ARPE-19 cells transfected with Vector, ALKBH5 or ALKBH5+sh-ZEB1#1; (B), Transwell assay examined ARPE-19 cell migration in different transfection groups; (C), EMT markers expressions were uncovered by RT-qPCR in different transfection groups.