Evaluation of the effect of the fructose, the MECL and losartan on anxiety like in the EPM. A: Number of entries into open arms. B: Time spent in open arms. The results are represented by the mean ± SEM (n = 6), the statistical analyzes were carried out by unidirectional ANOVA followed by Tukey’s post hoc test; the significance level is. * P <0.05, ** P <0.01, *** P <0.001. C. Curcuma longa, F. fructose, L. losartan.