Histopathological examination of rat liver tissues by hematoxylin and eosin: a. control rats and b.CSO-administrated rat are showing normal histological structure in portal area (arrow) and hepatic cells. c. DOX-treated rat showing marked thickening of the hepatic (Glisson’s) capsule with edema and few inflammatory cells infiltration, necrosis and degeneration of the subcapsular hepatocytes.d.CSO/DOX-treated rat showing few inflammatory cells infiltrating the portal areas and mild degeneration of the hepatic cells. e. CSO/DOX-treated rat showing good restoration of the hepatic cells with only mild degeneration of the hepatic cells, (X200).