Effect of different concentrations of ethanolic extract of Acacia modesta on liver function tests (A), hematological parameters (B) and arthritic score (C). A, Liver markers ALP, ALT and AST were calculated by one-way ANOVA and Dennett’s multiple comparison test. E-AM treated extracts showed a normal ALP, ALT and AST levels. B, Hematological parameters E-AM showed ameliorating effect on hematological parameters at a dose of 750 mg/kg. C, arthritic index the normal control group did not show any swelling throughout the study. Treatment with the E-AM and piroxicam effectively reduce the arthritic index in comparison to arthritis control group from day 16 to 28. The maximum arthritic index observed at 28th day that was restored by E-AM at 750mg/kg compared with low doses. ***, **, * showing P≤0.05, P≤ 0.01, P≤ 0.001.