(A) BHD treatment inhibited HG-induced apoptosis pathway in PC12 cells. The density of PI3K, p-PI3K, AKT, p-AKT, Bax, Bcl-2, and Caspase-3 were measured by Western Blot. (B) Quantitative data of PI3K, (C) p-PI3K, (D) AKT, (E) p-AKT, (F) Bax, (G) Bcl-2, (H) Bax/Bcl-2, (I) Caspase-3, and (J) Cleaved Caspase-3 are presented. 

Data are shown as mean ± SD (n=3). * P <0.05, ** P <0.01, vs. the control group; # P < 0.05, ## P < 0.01, vs. the HG group.