Fig. 2.

PTEN as a direct miR-26a-5p target. A: Effect of post-ischemic treatment with sevoflurane on PTEN mRNA expression (n=3). B (left): Effect of post-ischemic treatment with sevoflurane on the level of PTEN protein (n=3). C (right): The complementary relationship between miR-26a-5p and the 3’UTR of Wild-type PTEN. D: The luciferin reporter groups verified whether miR-26a-5p is a direct PTEN target (n=3). ** represents sham group V.S. I/R model group; ## represents I/R model group V.S. sevoflurane group P<0.01; and represents sevoflurane group V.S. sevoflurane+antamiR-26a-5p group P<0.01.