A, B, C, D shows section of kidney at the 5th week of the experiment. The kidney section revealed severe degeneration and necrosis of renal parenchyma, damage of renal tubules, infiltration of the inflammatory cells and severe congestion and absence of immature cancer cell aggregation (Damage of renal tubules: DRTs; renal cortex: RC; Renal medulla: RM; Glomeruli: G). (A. X 4, B. X10, C.X20, D. X40). (H and E).