Fig. 4.
The expression of SSTR2 protein in DRGs by western bolt. (A) SSTR2 expression in DRGs after Carrageenan injection. Mice sacrificed at 15min, 90 min, 1day and 4 day after Carrageenan injected in left- hind paw(L), compared with right-side untreated hind paw, showed up-regulated SSTR2 expression in DRG neurons at 15min and 90 min these two time points (no significant differences existed, respectively); However, 1day after injection of Carrageenan, SSTR2 protein showed down-regulated in left-side DRGs(L), after 4 day, The SSTR2 protein sharply reduced in left-side DRGs(L) compared to right-side DRGs(R). Error bars represent standard error of the mean±SEM. Significant differences are indicated by *, P<0.05; **. P<0.01 (n=5). (B) The expression of SSTR2 in DRGs on the basis of DR and SNI models. Tissues from ipsilateral hind paw DRGs (L) are compared with tissues from contralateral hind paw DRGs(R) after DR 1 week and SNI 3weeks surgery. SSTR2 expression are not showed significant variations in neither of these two models (n=5).