Depletion of YAP reversed the induced trastuzumab resistance in SK-BR-3-TR cells. (A) Protein expression of YAP and TAZ detected by western blotting. (B) Cell apoptosis analyzed by flow cytometry. (C) Cell viability detected by MTT assay. ** P<0.01 vs SK-BR-3-TS group. ## P<0.01 vs SK-BR-3-TR group (One way ANOVA).