Calculation of Damaged areas in proximal convoluted tubules in different animal groups. The graph demonstrating no proximal tubular damage in normal control. Whereas, there is a marked increase in damaged area in glycerol treated AKI group compared to the normal control (*p <0.001). A significant decrease in the damaged areas was observed in animals treated with CA as compared with the glycerol treated AKI group (*p <0.001) and nearly complete protection can be seen in CA-AuNPs treated groups at a relatively low dose (*p <0.001).