Effect of different concentrations of ethanolic extract of Acacia modesta on gene expression analysis (A), and antioxidative potential superoxide dismutase and catalase (B). The gene expression of several inflammatory biomarkers were evaluated following 28 days of study in wistar rats for mRNA expression of IL4, IL6, IL10, NF-κβ1, TNF-a, COX-2. In case of antioxidants SOD and CAT there was a significant decline of antioxidants compared to arthritic group. ***, **, * showing P≤0.05, P≤ 0.01, P≤ 0.001.