Biochemical assays in mice brain and CNS. The splenic cells from naïve mice were analyzed for proliferation and MOG challenged cytokines estimation. T-cell population were counted in PCB treated EAE mice. A, MDA, LPO and SOD activity were scored in PCB treated EAE mice; B, effect of PCB on cell viability of mice splenocytes; C, effect of PCB on MOG induced splenocytes cytokines level (IL-17, IL-6 IFN-γ and TGF-β) are quantified. For each group values were presented as mean ± SD. One way ANOVA followed by post hoc t-test were used for statistical analysis (significant at p ≤ 0.05).