Representative photomicrograph of sheep kidney sections stained with HandE (x200). (A) Congestion and dilatation of the intertubular blood vessels (arrow) along with mild interstitial fibrosis (asterisk). (B) Vasculitis in renal blood vessels with thickening (arrow) and fibrosis (asterisk) of the blood vessels wall with mononuclear leukocytic infiltration. (C) Glomerular tuft hypercellularity and segmentation (arrow). (D) Glomerular tuft shrinkage (arrow) with degenerative changes in renal tubules (arrowhead). (E) Vacuolar degeneration with desquamation of the tubular epithelial cells (arrowhead). (F) Hypercellularity of the glomerular tuft with hyperplasia of mesangial cells (arrow), reduced Bowman’s space, thickening, and hyalinization of Bowman’s capsule (arrowhead) associated with hyaline casts in tubular lumina (asterisk).