Fig. 7.
MiR-26a-5p inhibition expression level inhibits the anti-inflammatory effect of post-ischemia treatment with sevoflurane. A: Impact of antamiR-26a-5p+sevoflurane on TNF-α mRNA level in myocardial tissue of rats (n = 7). B: Impact of antamiR-26a-5p+sevoflurane on IL-1β mRNA level in myocardial tissue of rats (N = 7). C: Impact of antamiR-26a-5p+sevoflurane on IL-8 mRNA level in rat myocardial tissue (n = 7). D: Impact of antamiR-26a-5p+sevoflurane on ICAM-1 mRNA level in rat myocardial tissue (n = 7). E: Impact of antamiR-26a-5p+sevoflurane on VCAM-1 mRNA level in rat myocardial tissue (n = 7). We adopted RT-qPCR to detect the influences of different treatment methods on TNF-α, IL-1β, IL-8, ICAM-1 and VCAM-1 mRNA levels in rat myocardial tissue (n = 7). ** represents sham group V.S. I/R model group; ## represents I/R model group V.S. sevoflurane group P<0.01; and represents sevoflurane group V.S. sevoflurane+antamiR-26a-5p group P<0.01.