Nuclear morphology at the expected MI stage of GV cytoplasts reconstructed with GV, embryonic and somatic nuclei. DNA was stained with Hoechst 33342. A) GV cytoplast reconstructed with GV nucleus. Various abnormal nuclear morphology was observed in manipulated GV cytoplast reconstructed with embryonic/somatic at the expected MI stage. These include: condensed, scattered chromosomes (B), partially condensed chromosomes (C), formation of micronuclei and «pycnotic» nuclei (D), and interphase-like nuclei (E).