Effect of lathyrol on activation and expression of STAT3 and cleavage of caspase-3. (A) Hep-3B, (B) MHCC97-L, (C) A2780 and (D) taxol-resistant Hey-T30 cells were treated with lathyrol overnight and cell lysates were prepared using RIPA lysis buffer supplemented with 10%PMSF. The cell lysates were subjected to immunoblotting for the expression of p-STAT3, STAT3, and cleaved caspase-3. GAPDH was used a loading control.