Effect of different doses of MELV (125. 250 and 500 mg/kg bw) on histological section of liver and kidney tissue in male and female hamsters. (Black arrow) Moderate hepatic necrosis, (+) periportal lymphocyte infiltrate, (Red arrow) predominantly lymphocyte glomerular infiltrate, (Green arrow) sinusoidal dilatation, (Blue arrow) tubular atrophy.