Results of the open field test during a 2-min period for each group of rats.

(A) Slient period: total inactivity time; (B) Exercise time: total activity time; (C) Behavioral path: total travel distance; (D) Center residence time: time spent in the central area; (E) Corner residence time: time spent in the corners; (F) Side residence time: time spent on the side.

Notes: Data are presented as mean ± SD (n = 10 per group). Compared with Control group, ## P <0.01; Compared with Model group, * P <0.05, ** P <0.01.