The secondary structure of the protein and mRNA before and after the mutation at g. 64266710 G> C, g.64266715 G> C and g. 64237881 A> C. (A) Secondary protein structure before the mutation; (B) Secondary protein structure after the mutation; (C) mRNA secondary structure before the mutation; (D) mRNA secondary structure after the mutation. Note: The blue arrow refers to the g. 64266710 G> C and g.64266715 G> C locus; The red arrow refers to the g. 64237881 A> C locus.