Evaluation of the effect of the fructose, the MECL and losartan on the time spent in the quadrant where the platform was located during the acquisition phase. The results are represented by the mean ± SEM (n = 6), the statistical analyses were carried out by unidirectional ANOVA followed by Tukey’s post hoc test; the significance level is. * P <0.05, ** P <0.01, *** P <0.001. C. curcuma longa, F. fructose, L. losartan.